Edinburgh: We know that millions of cells, tissues and muscles die rapidly after a severe heart attack. Understanding this process in genetic depth will not only make it possible to cure it but will also pave the way for new cells to form. Now there has been a significant breakthrough in this regard which scientists have termed as a very important achievement.
Dr. Mary Burton of the University of Edinburgh Center for Cardiology and her colleagues have been considering genetic modification for some time after a heart attack. Hundreds of millions of cells die within seconds of a heart attack and a large part of the heart may become inactive, but genetic therapy may be possible after learning of genetic mutations.
Dr. Marie is considering endothelial progenitor cells (EPCs), the reproductive cells. Although made up of endothelial cells similar to the inner walls of the heart and arteries. These cells are now destroyed in heart attacks and other ailments, but can be repaired with EPC. Dr. Marie has revealed this in 2019.
They collected cells from the heart of some patients after a heart attack and identified genes in them that are activated when the heart cells and blood vessels are affected. Over the years, they have made it an atlas to repair blood vessels and the heart. This has never been done before.
According to scientists, by targeting these genes, the injured heart can be repaired. That is, as soon as the patient has a severe heart attack, the patient can be saved from further harm by injecting with gene therapy. In this way, the gene itself will be able to slowly restore and heal the heart.
In this system of nature, the zebrafish can repair its own heart. On the other hand, American scientists have studied the signals and pathways in the hearts of rats and pigs, by following which it is possible to restore the heart.
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